BIOPEP-UWM: Report

ID 10627
Name Glutamate carboxypeptidase II inhibitor
sequence
{C2:0}DED
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
4
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 419.3399 Monoisotopic mass 419.1170
IC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(=O)O)C(=O)O

InChI=1S/C15H21N3O11/c1-6(19)16-8(4-11(22)23)14(27)17-7(2-3-10(20)21)13(26)18-9(15(28)29)5-12(24)25/h7-9H,2-5H2,1H3,(H,16,19)(H,17,27)(H,18,26)(H,20,21)(H,22,23)(H,24,25)(H,28,29)/t7-,8-,9-/m0/s1

InChIKey=MUSWVJNGJMLAJU-CIUDSAMLSA-N


{C2:0} - Acetic acid - N-terminal modification (ID 130 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand N-Acetyl-Asp-Glu-Asp