BIOPEP-UWM: Report

ID 10628
Name Glutamate carboxypeptidase II inhibitor
sequence
{C2:0}DSG
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
4
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 319.2673 Monoisotopic mass 319.1011
IC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)O

InChI=1S/C11H17N3O8/c1-5(16)13-6(2-8(17)18)11(22)14-7(4-15)10(21)12-3-9(19)20/h6-7,15H,2-4H2,1H3,(H,12,21)(H,13,16)(H,14,22)(H,17,18)(H,19,20)/t6-,7-/m0/s1

InChIKey=CSVQZHJXQYTGJS-BQBZGAKWSA-N


{C2:0} - Acetic acid - N-terminal modification (ID 130 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand N-Acetyl-Asp-Ser-Gly