BIOPEP-UWM: Report

ID 10629
Name Glutamate carboxypeptidase II inhibitor
sequence
<C2:0>ED
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
3
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 304.2527 Monoisotopic mass 304.0902
EC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(=O)O)C(=O)O

InChI=1S/C11H16N2O8/c1-5(14)12-6(2-3-8(15)16)10(19)13-7(11(20)21)4-9(17)18/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7-/m0/s1

InChIKey=XOWJQZVPMDHJBN-BQBZGAKWSA-N


<C2:0> - Acetic acid - N-terminal modification (ID 130 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BindingDB: ID 50014189

BRENDA: Ligand N-Acetyl-Glu-Asp

ChEMBL: ID CHEMBL90464

ChemSpider: ID 23180732

J-GLOBAL: ID 200907085515666104

Nikkaji: ID J347.291D

PubChem: CID 14728461

ZINC: ID ZINC000013536906