BIOPEP-UWM: Report

ID 10630
Name Glutamate carboxypeptidase II inhibitor
sequence
{C2:0}EE
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
3
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 318.2792 Monoisotopic mass 318.1058
IC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C12H18N2O8/c1-6(15)13-7(2-4-9(16)17)11(20)14-8(12(21)22)3-5-10(18)19/h7-8H,2-5H2,1H3,(H,13,15)(H,14,20)(H,16,17)(H,18,19)(H,21,22)/t7-,8-/m0/s1

InChIKey=OLBUBQCXGZCOQZ-YUMQZZPRSA-N


{C2:0} - Acetic acid - N-terminal modification (ID 130 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BindingDB: ID 50014182

BRENDA: Ligand N-Acetyl-Glu-Glu

ChEMBL: ID CHEMBL91492

ChemSpider: ID 23180723

J-GLOBAL: ID 200907069432357937

Nikkaji: ID J347.289B

PubChem: CID 14728459

SureChEMBL: ID SCHEMBL2248714

ZINC: ID ZINC000026648612