BIOPEP-UWM: Report

ID 10631
Name Glutamate carboxypeptidase II inhibitor
sequence
{C2:0}DE
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
3
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 304.2527 Monoisotopic mass 304.0902
IC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7-/m0/s1

InChIKey=OPVPGKGADVGKTG-BQBZGAKWSA-N


{C2:0} - Acetic acid - N-terminal modification (ID 130 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BindingDB: ID 17658

BRENDA: Ligand N-Acetyl-Asp-Glu

CAS: Registry No 3106-85-2

ChEBI: ID 73688

ChEMBL: ID CHEMBL1329032

ChemSpider: ID 164080

Clinical Trials: compound ISOSPAGLUMIC ACID

DrugBank: ID DB08835

ECHA: ID 635-744-0

EPA CompTox: ID DTXSID3091535

FDA SRS: 1W8M12WXYL

FooDB: ID FDB022406

Guide to Pharmacology: ID 1405

HMDB: ID HMDB0001067

J-GLOBAL: ID 200907064777600204

KEGG: ID C12270

MarkerDB: ID MDB00029994

MedChemExpress: ID HY-100921

Metabolights: ID MTBLC73688

Metabolomics Workbench: ID 67852

Nikkaji: ID J22.752H

NSC: ID 758468

PubChem: CID 188803

SureChEMBL: ID SCHEMBL288514

UNII: ID 1W8M12WXYL

ZINC: ID ZINC000026648612