BIOPEP-UWM: Report

ID 10636
Name Glutamate carboxypeptidase II inhibitor
sequence
DA
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
2
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 204.1801 Monoisotopic mass 204.0743
EC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C)C(=O)O

InChI=1S/C7H12N2O5/c1-3(7(13)14)9-6(12)4(8)2-5(10)11/h3-4H,2,8H2,1H3,(H,9,12)(H,10,11)(H,13,14)/t3-,4-/m0/s1

InChIKey=DVUFTQLHHHJEMK-IMJSIDKUSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 7606); the BRENDA database; the ChEMBL database; the PubChem database; the SATPdb database
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010) according to the BRENDA database
Activator of Carbonic anhydrase (EC 4.2.1.1) according to the ChEMBL database; the PubChem database
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9492)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 230)
Umami peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 350)


Database reference:
ACToR: ID 13433-02-8

AHTPDB: ID 1688; 3090; 3095; 3139; 3239; 3470; 3835; 3895; 4413; 4541; 4693; 6592

BindingDB: ID 50169166

BIOPEP-UWM database of bioactive peptides: ID 7606; 9492

BIOPEP-UWM database of sensory peptides and amino acids: ID 230; 350

BRENDA: Ligand Asp-Ala

ChEBI: ID 73826

ChEMBL: ID CHEMBL17503

ChemIDplus: ID 3433-02-88

ChemSpider: ID 4590792

EROP-Moscow: ID E01842

J-GLOBAL: ID 200907068654974784

Metabolights: ID MTBLC73826

Nikkaji: ID J81.614K

PubChem: CID 5491963

SATPdb: ID satpdb20092

SureChEMBL: ID SCHEMBL3341838

ZINC: ID ZINC02123927