BIOPEP-UWM: Report

ID 10641
Name Glutamate carboxypeptidase II inhibitor
sequence
{E;5}E
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
2
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 276.2426 Monoisotopic mass 276.0953
IC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@]([H])(C(=O)O)CCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C10H16N2O7/c11-5(9(16)17)1-3-7(13)12-6(10(18)19)2-4-8(14)15/h5-6H,1-4,11H2,(H,12,13)(H,14,15)(H,16,17)(H,18,19)/t5-,6-/m0/s1

InChIKey=OWQDWQKWSLFFFR-WDSKDSINSA-N

{E;5} - glutamic acid bound via gamma carboxyl group (ID 77 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand gamma-Glu-Glu

CAS: Registry No 1116-22-9

ChEBI ID CHEBI:73705

Chemspider: ID 83831

ECHA: ID 214-233-2

EPA CompTox: ID DTXSID20912237

FooDB: ID FDB028415

Good Scents: ID rw1248021

HMDB: ID HMDB0011737

J-GLOBAL: ID 200907084266261895

KEGG: ID C05282

Metabolomics Workbench: ID 41509

Nikkaji: ID J203.335F

PubChem: CID 92865

UNII: ID 6018KCN7X2