BIOPEP-UWM: Report

ID 10643
Name Glutamate carboxypeptidase II inhibitor
sequence
EE

Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
2
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 276.2426 Monoisotopic mass 276.0953
EC50 :
0.00 µM



Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)CCC(=O)O)CCC(=O)O

InChI=1S/C10H16N2O7/c11-5(1-3-7(13)14)9(17)12-6(10(18)19)2-4-8(15)16/h5-6H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChIKey=KOSRFJWDECSPRO-WDSKDSINSA-N


Peptide found in chicken meat protein hydrolysate:

Maehashi K., Matsuzaki M., Yamamoto Y., Udaka, S. 1999, Isolation of peptides from an enzymatic hydrolysate of food proteins and characterization of their taste properties. Biosci. Biotech. Biochem., 63, 555-559


Inhibitor of Thymidylate synthase (EC 2.1.1.45) according to the BRENDA database
Inhibitor of Citrate-lyase deacetylase (EC 3.1.2.16) according to the BRENDA database
Inhibitor of Glutamate carboxypeptidase (EC 3.4.17.11) (MEROPS ID: M20.001) according to the BIOPEP-UWM database of bioactive peptides, the BRENDA database
Inhibitor of citrulline uptake in yeasts according to the ChEMBL database; the PubChem database
Peptide stimulating vasoactive substance release according to the BIOPEP-UWM database of bioactive pptides (ID 8329)

Umami peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 248)
Salty peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 249)
Bitterness suppressing peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 331)
Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 355)
Sweetness suppressing peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 368)




Database reference:
BindingDB: ID 50102260

BIOPEP-UWM database of bioactive peptides: ID 8329

BIOPEP-UWM database of sensory peptides and amino acids: ID 248; 249; 331; 355; 368

BRENDA: Ligand Glu-Glu

CAS: Registry No 3929-61-1

ChEBI: ID 5390

ChEMBL: ID CHEMBL318315

ChemSpider: ID 388598

EROP-Moscow: ID E01846

FooDB: ID FDB111863

HMDB: ID HMDB0028818

J-GLOBAL: ID 200907038579579762

KEGG Ligand: ID C01425

Metabolights: MTBLC5390

Metabolomics Workbench: ID 78782

Nikkaji: ID J364.668H

NMRShiftDB: ID 60022130

PubChem: CID 439500

SureChEMBL: ID SCHEMBL435318

ZINC: ID ZINC000001529201