BIOPEP-UWM: Report

ID 10649
Name Hypouricemic peptide
sequence
PEW

Function:
Hypouricemic activity in vivo in rats
 
Number of residues
3
Activity code
hur
Activity :
hypouricemic
Chemical mass 430.4533 Monoisotopic mass 430.1846
EC50 :
0.00 µM



Bibliographic data:
Authors
Qi X., Guan K., Liu C., Chen H., Ma Y., Wang R.
Title
Whey protein peptides PEW and LLW synergistically ameliorate hyperuricemia and modulate gut microbiota in potassium oxonate and hypoxanthine-induced hyperuricemic rats, J. Dairy Sci., 106, 7367-7381, 2023
Year Source
2023 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C21H26N4O6/c26-18(27)8-7-16(24-19(28)15-6-3-9-22-15)20(29)25-17(21(30)31)10-12-11-23-14-5-2-1-4-13(12)14/h1-2,4-5,11,15-17,22-23H,3,6-10H2,(H,24,28)(H,25,29)(H,26,27)(H,30,31)/t15-,16-,17-/m0/s1

InChIKey=ZTVCLZLGHZXLOT-ULQDDVLXSA-N



Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database

Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7) according to the BIOPEP-UWM Virtual database (ID 54)



Database reference:
AHTPDB: ID 2108, 3662

BioPepDB: ID biopep01038

BIOPEP-UWM Virtual: ID 54

ChEBI: ID 162291

Metabolomics Workbench: ID 84793

PubChem: CID 145457466

SATPdb: ID satpdb21959