BIOPEP-UWM: Report

ID 10653
Name Glutathione - Glutamate carboxypeptidase II inhibitor
sequence
{E;5}CG
Function:
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010)
 
Number of residues
3
Activity code
gluc2
Activity :
glutamate carboxypeptidase II inhibitor
Chemical mass 307.3239 Monoisotopic mass 307.0834
IC50 :
0.00 µM


Bibliographic data:
Authors
Robinson M. B., Blakely R. D., Couto R., Coyle J. T.
Title
Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. J. Biol. Chem., 262, 14498-14506, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@]([H])(C(=O)O)CCC(=O)N[C@@]([H])(CS)C(=O)NCC(=O)O

InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChIKey=RWSXRVCMGQZWBV-WDSKDSINSA-N


{E;5} - glutamic acid bound via γ-carboxyl group (ID 77 in the BIOPEP-UWM repository of amino acids and modifications)


Antioxidative peptide according to the ChEMBL database; the EROP-Moscow database


Database reference:
BiGG: ID 33669

BindingDB: ID 50422268

BioCyc: Compound GLUTATHIONE

Brenda: Ligand Glutathione

CAS: Registry No 70-18-8

ChEBI: ID 16856

ChEMBL: ID CHEMBL1543

Chemspider: ID 111188

DrugBank: ID DB00143

DrugCentral: ID 1312

ECHA: ID 200-725-4

EPA CompTox: ID DTXSID6023101

EROP-Moscow: ID E03922

FDA SRS: ID GAN16C9B8O

FooDB: ID FDB001498

Guide to Pharmacology: ID 6737

HMDB: ID HMDB0000125

J-GLOBAL: ID 200907050768514817

KEGG: ID C02471

KNApSAcK: ID C00001518

MarkerDB: ID MDB00000060

Metabolights: ID MTBLC16856

Metabolomics Workbench: ID 37087

METLIN: ID 44

Nikkaji: ID J10.686K

NMRShiftDB: ID 60020798

NSC: ID 758199

PDBe: ID GSH

Pharos Ligand: ID 82VDMK4PDWYL

ProbesDrugs: ID PD001337

PubChem: CID 124886

SureChEMBL: ID SCHEMBL9167

UNII: ID GAN16C9B8O

ZINC: ID ZINC000003830891