BIOPEP-UWM: Report

ID 10658
Name Inhibitor of tripeptidyl peptidase II
sequence
AAA
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
3
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 231.2483 Monoisotopic mass 231.1215
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O

InChI=1S/C9H17N3O4/c1-4(10)7(13)11-5(2)8(14)12-6(3)9(15)16/h4-6H,10H2,1-3H3,(H,11,13)(H,12,14)(H,15,16)/t4-,5-,6-/m0/s1

InChIKey: BYXHQQCXAJARLQ-ZLUOBGJFSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BRENDA database
Inhibitor of Cytosol alanyl aminopeptidase (EC 3.4.11.14) (MEROPS ID: M01.010) according to the BIOPEP-UWM database of bioactive peptides (ID 10612); the BRENDA database
Inhibitor of Xaa-Pro aminopeptidase (EC 3.4.11.9) (MEROPS ID: M24.005) according to the BRENDA database
Inhibitor of Dipeptidyl-peptidase III (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BRENDA database

Sweet peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 256)


Database reference:
ACToR: ID 5874-90-8

BindingDB: ID 50169192

BIOPEP-UWM database of bioactive peptides: ID 10612

BIOPEP-UWM database of sensory peptides and amino acids: ID 256

BRENDA: Ligand Ala-Ala-Ala

ChEBI: ID 73313

ChEMBL: ID CHEMBL189368

ChemSpider: ID 4585992

PubChem: ID 5478845

ZINC: ID ZINC04533743