BIOPEP-UWM: Report

ID 10659
Name Inhibitor of tripeptidyl peptidase II
sequence
AA
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 160.1706 Monoisotopic mass 160.0845
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C)C(=O)N[C@@H](C)C(=O)O

InChI=1S/C6H12N2O3/c1-3(7)5(9)8-4(2)6(10)11/h3-4H,7H2,1-2H3,(H,8,9)(H,10,11)/t3-,4-/m0/s1

InChIKey=DEFJQIDDEAULHB-IMJSIDKUSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 7590), the BRENDA database; the ChEMBL database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP database of bioactive peptides (ID 8637); the BRENDA database; the EROP-Moscow database
Inhibitor of Cytosol alanyl aminopeptidase (EC 3.4.11.14) (MEROPS ID: M24.005) according to the BIOPEP-UWM database of bioactive peptides (ID 10611); the BRENDA database
Inhibitor of D-Ala-D-Ala Dipeptidase (EC 3.4.13.22) (MEROPS ID: M15.011) according to the BRENDA database
Inhibitor of Peptide-transporting ATPase (EC 3.6.3.43) according to the BRENDA database
Activator of Carbonic anhydrases (EC 4.2.1.1) according to the ChEMBL database
Antibacterial peptide according to the ChEMBL database

Sweet peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 241)


Database reference:
AHTPDB: ID 1680; 2982; 3229; 3464; 3552; 3608; 3832; 3885; 4431; 4538; 4684; 5134; 6112; 6576

BioPepDB: ID biopep00002

BIOPEP-UWM database of bioactive peptides: ID 7590, 8637; 10141; 10611

BIOPEP-UWM database of sensory peptides and amino acids: ID 241

BRENDA: Ligand Ala-Ala

ChEBI: ID 72816

ChEMBL: ID CHEMBL17697

ChemIDplus: ID 001948318

ChemSpider: ID 4588478

EPA DSSTox: ID DTXSID00173127

EROP-Moscow: ID E06348

FeptideDB: ID 7590; 8637

FooDB: ID FDB003740

Golm Metabolome Database: ID DF49DD8A-D390-4F75-8C8A-3A07EF07DD48

HMDB: ID HMDB0028680

J-GLOBAL: ID 200907012990949768

KNApSAcK: ID C00017958

MeSH; ID 67002956; term alanylalanine

Metabolomics Workbench: ID 78656

Nikkaji: ID J47.023F

NIST Chemistry WebBook: Compound L-Alanine, N-L-alanyl-

PlantPepDB: ID PPepDB_1

PubChem: CID 6992372

SAPdb: ID 1016

SATPdb: ID satpdb12967

SpectraBase: Compound L-Alanyl-L-alanine

ZINC: ID ZINC01575493