BIOPEP-UWM: Report

ID 10660
Name Inhibitor of tripeptidyl peptidase II
sequence
AAPA
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
4
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 328.3632 Monoisotopic mass 328.1741
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)O

InChI=1S/C14H24N4O5/c1-7(15)11(19)16-8(2)13(21)18-6-4-5-10(18)12(20)17-9(3)14(22)23/h7-10H,4-6,15H2,1-3H3,(H,16,19)(H,17,20)(H,22,23)/t7-,8-,9-,10-/m0/s1

InChIKey=KHANLXYXMOODOB-XKNYDFJKSA-N


Database reference:
BRENDA: Ligand Ala-Ala-Pro-Ala

CAS: Registry No 53620-20-5

ChEMBL: ID CHEMBL2371250

EPA CompTox: ID DTXSID60432904

PubChem: CID 9923480

SureChEMBL: ID SCHEMBL10749206

ZINC: ID ZINC000004899722