BIOPEP-UWM: Report

ID 10661
Name Inhibitor of tripeptidyl peptidase II
sequence
AF
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 236.2664 Monoisotopic mass 236.1157
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C12H16N2O3/c1-8(13)11(15)14-10(12(16)17)7-9-5-3-2-4-6-9/h2-6,8,10H,7,13H2,1H3,(H,14,15)(H,16,17)/t8-,10-/m0/s1

InChIKey=OMNVYXHOSHNURL-WPRPVWTQSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8759)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 7583)


Database reference:
AHTPDB: ID 1271; 1363; 1410; 1503; 1678; 1892; 1896; 2591; 2747; 3031; 3222; 3344; 3419; 3465; 3790; 3846; 3886; 4441; 4496; 4679; 5429; 5787; 6211; 6569

BindingDB: ID 50188503

BIOPEP-UWM database of bioactive peptides: ID 7583; 8759

BIOPEP-UWM database of sensory peptides and amino acids: ID 50

BRENDA: Ligand Ala-Phe

CAS: Registry No 3061-90-3

ChEBI: ID 73807

ChEMBL: ID CHEMBL57338

ChemIDPlus: ID 3061-90-3

ChemSpider ID: 87414

DFBP: ID DFBPACEI0116;

EPA CompTox: ID DTXSID801312981

EROP-Moscow: ID E04069; E03700

FooDB: ID FDB111753

HMDB: ID HMDB0028694

J-GLOBAL: ID 200907056679638527

MeSH: Terms Ala-Phe; alanylphenylalanine; L-alanyl-L-phenylalanine

Metabolights: ID MTBLC73807

Metabolomics Workbench: ID 78669

Nikkaji: ID J80.627G

NMRShiftDB: ID 60022205

PlantPepDB: ID PPepDB_241

ProbesDrugs: ID PD165131

PubChem: ID 6992394

ZINC: ID ZINC01575524