BIOPEP-UWM: Report

ID 10670
Name Antiviral peptide
sequence
IPAVF
Function:
Inhibitor of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007)
 
Number of residues
5
Activity code
avi
Activity :
antiviral
Chemical mass 545.6692 Monoisotopic mass 545.3203
EC50 :
0.00 µM


Bibliographic data:
Authors
Gambacorta N., Caputo L., Quintieri L., Monaci L., Ciriaco F., Nicolotti O.
Title
Rational discovery of antiviral whey protein-derived small peptides targeting the SARS-CoV-2 main protease. Biomedicines, 10, 1067, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H]([C@H](CC)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O

InChI=1S/C28H43N5O6/c1-6-17(4)22(29)27(37)33-14-10-13-21(33)25(35)30-18(5)24(34)32-23(16(2)3)26(36)31-20(28(38)39)15-19-11-8-7-9-12-19/h7-9,11-12,16-18,20-23H,6,10,13-15,29H2,1-5H3,(H,30,35)(H,31,36)(H,32,34)(H,38,39)/t17-,18-,20-,21-,22-,23-/m0/s1

InChIKey=RDMIXXDHHVQQKJ-PPSMKJHDSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactived peptides (ID 10672); the DFBP database; the MBPDB database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8620); the DFBP database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (D 502); the EROP-Moscow database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8620, 10672

BIOPEP-UWM database of sensory peptides and amino acids: ID 502

ChemSpider: ID 9401616

DFBP: ID DFBPACEI0120; DFBPDPIV0045; DFBPMUFU0051

EROP-Moscow: ID E23519

FeptideDB: ID 8620

J-GLOBAL: ID 201407044223295433

MBPDB: Peptide IPAVF

Nikkaji: ID J3.312.224A

PubChem: CID 11226563