BIOPEP-UWM: Report

ID 10675
Name Hypouricemic peptide
sequence
VYPFPGPI
Function:
Hypouricemic activity in vivo in rats
 
Number of residues
8
Activity code
hur
Activity :
hypouricemic
Chemical mass 889.0454 Monoisotopic mass 888.4730
EC50 :
0.00 µM


Bibliographic data:
Authors
Qi X., Chen H., Guan K., Wang R., Ma Y.
Title
Anti-hyperuricemic and nephroprotective effects of whey protein hydrolysate in potassium oxonate induced hyperuricemic rats. J. Sci. Food Agric., 101, 4916–4924, 2021
Year Source
2021 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)O

InChI=1S/C46H64N8O10/c1-5-28(4)39(46(63)64)51-42(59)35-15-9-21-52(35)37(56)26-48-40(57)34-14-10-22-53(34)44(61)32(24-29-12-7-6-8-13-29)49-41(58)36-16-11-23-54(36)45(62)33(50-43(60)38(47)27(2)3)25-30-17-19-31(55)20-18-30/h6-8,12-13,17-20,27-28,32-36,38-39,55H,5,9-11,14-16,21-26,47H2,1-4H3,(H,48,57)(H,49,58)(H,50,60)(H,51,59)(H,63,64)/t28-,32-,33-,34-,35-,36-,38-,39-/m0/s1

InChIKey: MJFASUNIWIJBFR-YIUNQBEOSA-N


Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001) according to the BIOPEP-UWM database of bioactive peptides (ID 2615), the DFBP database; the EROP-Moscow database, the MBPDB database
Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 7492), the DFBP database; the EROP-Moscow database, the MBPDB database


Database reference:
AHTPDB: ID 3407, 6502

BIOPEP-UWM database of bioactive peptides: ID 2615; 7492

DFBP: ID DFBPACEI0666; DFBPOPIO0112; DFBPOPIO0113; DFBPOPIO0114; DFBPPEPI0011; DFBPPEPI0046; DFBPPEPI0047; DFBPMUFU0150

EROP-Moscow: ID E14659

MBPDB: Peptide VYPFPGPI

PepBank: Peptide VYPFPGPI

PubChem: CID 134826889

SATPdb: ID satpdb10777