BIOPEP-UWM: Report

ID 10699
Name ACE 2 activator
sequence
PRY

Function:
Activator of Angiotensin 2-converting enzyme (ACE2) (EC 3.4.17.23) (MEROPS ID: M02.006)
 
Number of residues
3
Activity code
aac2
Activity :
ACE 2 activator
Chemical mass 434.4882 Monoisotopic mass 434.2271
EC50 :
0.00 µM



Bibliographic data:
Authors
Wang Z., Fan H., Bao X., Wu J.
Title
Angiotensin-converting enzyme 2 activation is not a common feature of angiotensin-converting enzyme inhibitory peptides. J. Agric. Food Chem., 71, 8867−8876, 2023
Year Source
2023 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C20H30N6O5/c21-20(22)24-10-2-4-15(25-17(28)14-3-1-9-23-14)18(29)26-16(19(30)31)11-12-5-7-13(27)8-6-12/h5-8,14-16,23,27H,1-4,9-11H2,(H,25,28)(H,26,29)(H,30,31)(H4,21,22,24)/t14-,15-,16-/m0/s1

InChIKey=OYEUSRAZOGIDBY-JYJNAYRXSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 3536); the BRENDA database; the DFBP database; the EROP-Moscow database
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID: A01.007) according to the BRENDA database; the DFBP database




Database reference:
AHTPDB: ID 1595, 5619, 6453,

BIOPEP-UWM database of bioactive peptides: ID 3536

BRENDA: Ligand Pro-Arg-Tyr

ChEBI: ID 162094

DFBP: ID DFBPACEI0578; DFBPRENI0038; DFBPMUFU0337

EROP-Moscow: ID E09263

Metabolomics Workbench: ID 84694

PlantPepDB: ID PPepDB_3835

PubChem: CID 145457395

SATPdb: ID satpdb22905