BIOPEP-UWM: Report

ID 10701
Name Renin inhibitor
sequence
WG
Function:
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID: A01.007)
 
Number of residues
2
Activity code
ren
Activity :
renin inhibitor
Chemical mass 261.2759 Monoisotopic mass 261.1110
EC50 :
0.00 µM


Bibliographic data:
Authors
Fu Y., Alashi A. M., Young J. F., Therkildsen M., Aluko R. E.
Title
Enzyme inhibition kinetics and molecular interactions of patatin peptides with angiotensin I-converting enzyme and renin. Int. J. Biol. Macromol., 101, 207-213, 2017
Year Source
2017 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)NCC(=O)O

InChI=1S/C13H15N3O3/c14-10(13(19)16-7-12(17)18)5-8-6-15-11-4-2-1-3-9(8)11/h1-4,6,10,15H,5,7,14H2,(H,16,19)(H,17,18)/t10-/m0/s1

InChIKey=UYKREHOKELZSPB-JTQLQIEISA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 3536); the BRENDA database; the DFBP database; the EROP-Moscow database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8697)
Antioxidant peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9082)


Database reference:
AHTPDB: ID 1485, 3091, 3816, 4051, 4407, 4522, 4695, 6599

BindingDB: ID 50188498

BioPepDB: ID biopep01517

BIOPEP-UWM database of bioactive peptides: ID 7613; 8697; 9082

BRENDA: Ligand Trp-Gly

CAS: Registry No 7360-09-0

ChEBI: ID 74870

ChEMBL: ID CHEMBL327588

ChemSpider: ID 87619

DFBP: ID DFBPRENI0039, DFBPACEI1621, DFBPACEI1779, DFBPACEI2209, DFBPANOX0725, DFBPMUFU0460

ECHA: ID 695-834-0

EPA CompTox: ID DTXSID701319027

EROP-Moscow: ID E10396

FDA SRS: ID GLE75A3004

GSRS: ID b486938d-35e5-46e5-b6a1-d805a1b9b4b6

J-GLOBAL: ID 200907023317662394

MeSH: Terms Trp-Gly; tryptophanylglycine; tryptophylglycine

Metabolights: ID MTBLC74870

Metabolomics Workbench: ID 79003

Nikkaji: ID J149.653K

NMRShiftDB: ID 80004542

PlantPepDB: ID PPepDB_3744

PubChem: CID 97054

SATPdb: ID satpdb11095

SureChEMBL: ID SCHEMBL8699875

UNII: ID GLE75A3004

ZINC: ID ZINC000002384992