BIOPEP-UWM: Report

ID 10707
Name ACE inhibitor
sequence
VENLHLPLPLL
Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
11
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1257.5168 Monoisotopic mass 1256.7469
IC50 :
175.00 µM


Bibliographic data:
Authors
Robert M. C., Razaname A., Mutter M., Juillerat M. A.
Title
Identification of angiotensin-I-converting enzyme inhibitory peptides derived from sodium caseinate hydrolysates produced by Lactobacillus helveticus NCC 2765. J. Agric. Food. Chem., 52, 6923-6931, 2004
Year Source
2004 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C60H100N14O15/c1-30(2)21-38(66-54(82)41(27-47(61)75)68-50(78)37(17-18-48(76)77)65-57(85)49(62)35(11)12)51(79)67-40(26-36-28-63-29-64-36)53(81)70-42(23-32(5)6)58(86)74-20-14-16-46(74)56(84)71-43(24-33(7)8)59(87)73-19-13-15-45(73)55(83)69-39(22-31(3)4)52(80)72-44(60(88)89)25-34(9)10/h28-35,37-46,49H,13-27,62H2,1-12H3,(H2,61,75)(H,63,64)(H,65,85)(H,66,82)(H,67,79)(H,68,78)(H,69,83)(H,70,81)(H,71,84)(H,72,80)(H,76,77)(H,88,89)/t37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,49-/m0/s1

InChIKey=DBHLZNQDTOOIDF-PTPXOIFGSA-N

Anticancer peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8317), the DFBP database


Database reference:
AHTPDB: ID ahtpdb_6946

BIOPEP-UWM database of bioactive peptides ID 8317

DFBP: ID DFBPACEI1438; DFBPANCA0094; DFBPANCA0109; DFBPMUFU0382

EROP-Moscow: ID E09176

MBPDB: Peptide VENLHLPLPLL

SATPdb: ID satpdb15620