BIOPEP-UWM: Report

ID 10718
Name ACE inhibitor
sequence
FK
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 293.3605 Monoisotopic mass 293.1734
IC50 :
265.43 µM


Bibliographic data:
Authors
Huang G.-J., Lu T., Chiu C., Chen H., Wu C., Lin Y., Hsieh W., Liao J., Sheu M. Lin Y.
Title
Sweet potato storage root defensin and its tryptic hydrolysates exhibited angiotensin converting enzyme inhibitory activity in vitro. Bot. Stud., 52, 257-264, 2011
Year Source
2011 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C15H23N3O3/c16-9-5-4-8-13(15(20)21)18-14(19)12(17)10-11-6-2-1-3-7-11/h1-3,6-7,12-13H,4-5,8-10,16-17H2,(H,18,19)(H,20,21)/t12-,13-/m0/s1

InChIKey=FADYJNXDPBKVCA-STQMWFEESA-N


Hypouricemic activity according to the BIOPEP-UWM database of bioactive peptides


Database reference:
BRENDA: Ligand Phe-Lys

CAS: Registry No 6456-72-0

ChEBI: ID 141443

ChemSpider: ID 76963305

EROP-Moscow: ID E01598

HMDB: ID HMDB0029000

J-GLOBAL: ID 200907074066868471

Metabolomics Workbench: ID 78927

Nikkaji: ID J81.224B

PlantPepDB: ID PPepDB_38

PubChem: CID 15607820