BIOPEP-UWM: Report

ID 10731
Name Hypotensive peptide
sequence
FY
Function:
Lowering blood pressure in rats
 
Number of residues
2
Activity code
hyp
Activity :
hypotensive
Chemical mass 328.3616 Monoisotopic mass 328.1418
EC50 :
0.00 µM


Bibliographic data:
Authors
Sato M., Hosokawa T., Yamaguchi T., Nakano T., Muramoto K., Kahara T., Funayama K., Kobayashi A., Nakano T.
Title
Angiotensin I-converting enzyme inhibitory peptides derived from wakame (Undaria pinnatifida) and their antihypertensive effect in spontaneously hypertensive rats. J. Agric. Food. Chem., 50, 6245-6252, 2002
Year Source
2002 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI: InChI=1S/C18H20N2O4/c19-15(10-12-4-2-1-3-5-12)17(22)20-16(18(23)24)11-13-6-8-14(21)9-7-13/h1-9,15-16,21H,10-11,19H2,(H,20,22)(H,23,24)/t15-,16-/m0/s1

InChIKey: FSXRLASFHBWESK-HOTGVXAUSA-N


Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides
Inhibitor of alpha-amylase (EC 3.2.1.1) according to the BIOPEP-UWM database of bioactive peptides
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 3556); the BRENDA database; the ChEMBL database; the DFBP database; the EROP-Moscow database; the PlantPepDB database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 478); the ChEMBL database (ID CHEMBL54572); the PubChem database (ID 515709)


Database reference:
AHTPDB: ID 1136; 1413; 1442; 1446; 1457; 1472; 1810; 1817; 1857; 2654; 2672; 2685; 2775; 2883; 3880; 3913; 4254; 4258; 4731; 4950; 5148; 5587; 5741; 5774; 5808; 6260; 6270; 6469; 6876

BIOPEP-UWM database of bioactive peptides: ID 3556

BIOPEP-UWM database of sensory peptides and amino acids: ID 478

BRENDA: Ligand Phe-Tyr

CAS: Registry No 17355-18-9

ChEBI: ID 73637

ChEMBL: ID CHEMBL54572

ChemSpider: ID 449878

DFBP: ID DFBPACEI0608; DFBPANHY0617; DFBPANHY0626; DFBPANHY0834; DFBPANHY0944; DFBPANHY0952; DFBPMUFU0231

EPA DSSTox: ID DTXCID40284746

EROP-Moscow: ID E00283

FooDB: ID FDB112023

HMDB: ID HMDB0029007

J-GLOBAL: ID 200907027277040714

Metabolomics Workbench: ID 78934

NIAID: ID 192291

Nikkaji: ID J366.936J

ParaPep: ID 1532; 1560

PlantPepDB: ID PPepDB_3722

PubChem: CID 515709

SATPdb: ID satpdb15002

ZINC: ID ZINC02384778