BIOPEP-UWM: Report

ID 10752
Name Inhibitor of tripeptidyl peptidase II
sequence
GWM
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
3
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 392.4727 Monoisotopic mass 392.1513
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C18H24N4O4S/c1-27-7-6-14(18(25)26)22-17(24)15(21-16(23)9-19)8-11-10-20-13-5-3-2-4-12(11)13/h2-5,10,14-15,20H,6-9,19H2,1H3,(H,21,23)(H,22,24)(H,25,26)/t14-,15-/m0/s1

InChIKey=RJVZMGQMJOQIAX-GJZGRUSLSA-N


Database reference:
BRENDA: Ligand Gly-Trp-Met

ChEBI: ID 164091

J-GLOBAL: ID 201207019813655592

MeSH: Terms Gly-Trp-Met; glycyl-tryptophyl-methionine

Metabolomics Workbench: ID 82208

Nikkaji: ID J3.107.071F

PubChem: CID 54270644