BIOPEP-UWM: Report

ID 10753
Name Inhibitor of tripeptidyl peptidase II
sequence
GVF
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
3
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 321.3706 Monoisotopic mass 321.1683
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C16H23N3O4/c1-10(2)14(19-13(20)9-17)15(21)18-12(16(22)23)8-11-6-4-3-5-7-11/h3-7,10,12,14H,8-9,17H2,1-2H3,(H,18,21)(H,19,20)(H,22,23)/t12-,14-/m0/s1

InChIKey=BNMRSWQOHIQTFL-JSGCOSHPSA-N


Database reference:
BRENDA: Ligand Gly-Val-Phe

CAS: Registry No 82985-55-5

ChEBI: ID CHEBI:164173

ChEMBL: ID CHEMBL2371249

ChemSpider: ID 5383046

EPA CompTox: ID DTXSID80427216

J-GLOBAL: ID 200907016818062498

Metabolomics Workbench: ID 82249

PubChem: CID 7020090

ZINC: ID ZINC000002561048