BIOPEP-UWM: Report

ID 10758
Name Inhibitor of tripeptidyl peptidase II
sequence
V{Nva}{~!C1}
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
3
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 229.3183 Monoisotopic mass 229.1785
IC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@H](CCC)C(=O)NC

InChI=1S/C11H23N3O2/c1-5-6-8(10(15)13-4)14-11(16)9(12)7(2)3/h7-9H,5-6,12H2,1-4H3,(H,13,15)(H,14,16)/t8-,9-/m0/s1

InChIKey=CKHZFBGXQXQERD-IUCAKERBSA-N


{Nva} - Norvaline (ID 230 in the BIOPEP-UWM repository of amino acids and modifications)
{~!C1} - C-terminal aminomethane (ID 131 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand Val-Nvl-NHCH3

ChEMBL: ID CHEMBL2371235

ChemSpider: ID 8903468

PubChem: CID 10728135

ZINC: ID ZINC000013805235