BIOPEP-UWM: Report

ID 10759
Name Inhibitor of tripeptidyl peptidase II
sequence
V{Nva}
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 216.2766 Monoisotopic mass 216.1469
IC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@H](CCC)C(=O)O

InChI=1S/C10H20N2O3/c1-4-5-7(10(14)15)12-9(13)8(11)6(2)3/h6-8H,4-5,11H2,1-3H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1

InChIKey=MLWJOEUDMIFEFJ-YUMQZZPRSA-N


{Nva} - Norvaline (ID 230 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand Val-Nvl-OH

ChEMBL: ID CHEMBL2371261

ChemSpider: ID 22903405

PubChem: CID 45049836

SureChEMBL: ID SCHEMBL8492399

ZINC: ID ZINC000004761034