BIOPEP-UWM: Report

ID 10760
Name Inhibitor of tripeptidyl peptidase II
sequence
IPI
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
3
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 341.4445 Monoisotopic mass 341.2307
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N1[C@H](C(=O)N[C@H](C(=O)O)[C@H](CC)C)CCC1)[C@H](CC)C

InChI=1S/C17H31N3O4/c1-5-10(3)13(18)16(22)20-9-7-8-12(20)15(21)19-14(17(23)24)11(4)6-2/h10-14H,5-9,18H2,1-4H3,(H,19,21)(H,23,24)/t10-,11-,12-,13-,14-/m0/s1

InChIKey=JNTMAZFVYNDPLB-PEDHHIEDSA-N


Inhibitor of tripeptidyl aminopeptidase (MEROPS ID: S08.A56) according to the ChEMBL database
Inhibitor of Tripeptidyl peptidase 2 (EC 3.4.14.10) (MEROPS ID: S08.090) according to the BRENDA database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database


Database reference:
ACToR: ID 90614-48-5

AHTPDB: ID 2290

BindingDB: ID 50229666

BIOPEP-UWM database of bioactive peptides: ID 3167

BRENDA: Ligand Ile-Pro-Ile; Ile-Pro-Ile-OH

CAS: Registry No 90614-48-5

ChEBI: ID 93213

ChemBank: ID KBio3_003020, SPBio_001439, Spectrum2_001480, Spectrum3_001838

ChEMBL: ID CHEMBL214381

ChemIDplus: ID 090614485

ChemSpider: ID 85449

DFBP: ID DFBPDPIV0159

EPA CompTox: ID DTXSID80920277

EROP-Moscow: ID E09227

FeptideDB: ID 3167

J-GLOBAL: ID 200907012372258533

MeSH: terms diprotin A; Ile-Pro-Ile; isoleucyl-prolyl-isoleucine

Metabolomics Workbench: ID 82945

MMDB: ID 33482.3

Natural Product Atlas: ID NPA020918

Nikkaji: ID J122.663K

NMRShiftDB: ID 70109396

ProbesDrugs: ID PD079971

PubChem: CID 94701

SATPdb: ID satpdb25992

SureChEMBL: ID SCHEMBL6404766

Wikidata: Q27164930

ZINC: ID ZINC04899477