BIOPEP-UWM: Report

ID 10780
Name ACE inhibitor
sequence
GLFF

Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 482.5706 Monoisotopic mass 482.2521
IC50 :
310.00 µM



Bibliographic data:
Authors
Ma K., Wang Y., Wang M., Wang Z., Wang X., Ju X., He R.
Title
Antihypertensive activity of the ACE–renin inhibitory peptide derived from Moringa oleifera protein. Food Funct., 12, 8994–9006, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C26H34N4O5/c1-17(2)13-20(28-23(31)16-27)24(32)29-21(14-18-9-5-3-6-10-18)25(33)30-22(26(34)35)15-19-11-7-4-8-12-19/h3-12,17,20-22H,13-16,27H2,1-2H3,(H,28,31)(H,29,32)(H,30,33)(H,34,35)/t20-,21-,22-/m0/s1

InChIKey=UNAXVUPZIOWDMR-FKBYEOEOSA-N


Hypotensive peptide according to the BIOPEP-UWM database of bioactive peptides
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID: A01.007) according to the BIOPEP-UWM database of bioactive peptides; the DFBP database



Database reference:
DFBP: ID DFBPACEI2222; DFBPRENI0041; DFBPANHY0996; DFBPMUFU0649