BIOPEP-UWM: Report

ID 10782
Name Hypotensive peptide
sequence
GLFF

Function:
Peptide lowering blood pressure in rats
 
Number of residues
4
Activity code
hyp
Activity :
hypotensive
Chemical mass 482.5706 Monoisotopic mass 482.2521
EC50 :
0.00 µM



Bibliographic data:
Authors
Ma K., Wang Y., Wang M., Wang Z., Wang X., Ju X., He R.
Title
Antihypertensive activity of the ACE–renin inhibitory peptide derived from Moringa oleifera protein. Food Funct., 12, 8994–9006, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C26H34N4O5/c1-17(2)13-20(28-23(31)16-27)24(32)29-21(14-18-9-5-3-6-10-18)25(33)30-22(26(34)35)15-19-11-7-4-8-12-19/h3-12,17,20-22H,13-16,27H2,1-2H3,(H,28,31)(H,29,32)(H,30,33)(H,34,35)/t20-,21-,22-/m0/s1

InChIKey=UNAXVUPZIOWDMR-FKBYEOEOSA-N


Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID: A01.007) according to the BIOPEP-UWM database of bioactive peptides; the DFBP database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides; the DFBP database



Database reference:
DFBP: ID DFBPACEI2222; DFBPRENI0041; DFBPANHY0996; DFBPMUFU0649