BIOPEP-UWM: Report

ID 10791
Name ACE inhibitor
sequence
GPTGPAGP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
8
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 652.6948 Monoisotopic mass 652.3170
IC50 :
262.98 µM



Bibliographic data:
Authors
Cao J., Xiang B., Dou B., Hu J., Zhang L., Kang X., Lyu M., Wang S.
Title
Novel angiotensin-converting enzyme-inhibitory peptides obtained from Trichiurus lepturus: preparation, identification and potential antihypertensive mechanism. Biomolecules, 14, 581, 2024
Year Source
2024 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C28H44N8O10/c1-15(24(41)30-13-22(40)36-11-5-8-19(36)28(45)46)32-25(42)17-6-4-10-35(17)21(39)14-31-27(44)23(16(2)37)33-26(43)18-7-3-9-34(18)20(38)12-29/h15-19,23,37H,3-14,29H2,1-2H3,(H,30,41)(H,31,44)(H,32,42)(H,33,43)(H,45,46)/t15-,16+,17-,18-,19-,23-/m0/s1

InChIKey=PDNNLKVLMMGHHL-IZDYBHSSSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001

Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides



Database reference:
BIOPEP-UWM database of bioactive peptides