BIOPEP-UWM: Report

ID 10796
Name Inhibitor of tripeptidyl peptidase II
sequence
MM
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 280.4088 Monoisotopic mass 280.0911
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C10H20N2O3S2/c1-16-5-3-7(11)9(13)12-8(10(14)15)4-6-17-2/h7-8H,3-6,11H2,1-2H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1

InChIKey=ZYTPOUNUXRBYGW-YUMQZZPRSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8833)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9085)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9086)


Database reference:
BindingDB: ID 50350482

BIOPEP-UWM database of bioactive peptides: ID 8833; 9085; 9086

BRENDA: Ligand Met-Met

ChEBI: ID 74707

ChEMBL: ID CHEMBL1222165

ChemSpider: ID 5361185

DFBP: ID DFBPACEI1781

J-GLOBAL: ID 200907019952150718

Metabolights: ID MTBLC74707

Nikkaji: ID J81.378H

PubChem: CID 6993082

SureChEMBL: ID SCHEMBL1157691

Wikidata: ID Q27144845

ZINC: ID ZINC01605257