BIOPEP-UWM: Report

ID 10797
Name Inhibitor of tripeptidyl peptidase II
sequence
VV
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 216.2766 Monoisotopic mass 216.1469
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)O

InChI=1S/C10H20N2O3/c1-5(2)7(11)9(13)12-8(6(3)4)10(14)15/h5-8H,11H2,1-4H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1

InChIKey=KRNYOVHEKOBTEF-YUMQZZPRSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 3183)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database

Umami peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 259);
Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 328); the ChEMBL database; the PubChem database


Database reference:
ACToR: ID 41049-53-0

AHTPDB: ID 3849

BindingDB: ID 50188521

BIOPEP-UWM database of bioactive peptides: ID 3183

BIOPEP-UWM database of sensory peptides and amino acids: ID 259; 328

BRENDA: Ligand Val-Val

Cambridge Structural Database: ID 290258

CAS: Registry No 3918-94-3

ChEBI: ID 73704

ChEMBL: ID CHEMBL54552

ChemSpider: ID 96710

EPA DSSTox: ID DTXCID601387837

EROP-Moscow: ID E09237

FeptideDB: ID 3183

FooDB: ID FDB112141

HMDB: ID HMDB0029140

J-GLOBAL: ID 200907038164816513

MeSH:Terms L-valyl-L-valine; Val-Val; valylvaline

Metabolights: ID MTBLC73704

Metabolomics Workbench: ID 79055

MMDB: ID 3226.3

Nikkaji: ID J364.680G

PubChem: ID 107475

SATPdb: ID satpdb12649

SureChEMBL: ID SCHEMBL4582286

Wikidata: Q27143934

ZINC: ID ZINC000001848346