BIOPEP-UWM: Report

ID 10798
Name Inhibitor of tripeptidyl peptidase II
sequence
MY
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 312.3849 Monoisotopic mass 312.1139
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCSC)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C14H20N2O4S/c1-21-7-6-11(15)13(18)16-12(14(19)20)8-9-2-4-10(17)5-3-9/h2-5,11-12,17H,6-8,15H2,1H3,(H,16,18)(H,19,20)/t11-,12-/m0/s1

InChIKey=PESQCPHRXOFIPX-RYUDHWBXSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8838)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 3388); the EROP-Moscow database
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8090)


Database reference:
AHTPDB: ID 1095, 1357, 2792, 3997, 4726, 5166, 5615, 6173, 6372

BIOPEP-UWM database of bioactive peptides: ID 3388; 8090; 8838

BRENDA: Ligand Met-Tyr-OH

CAS: Registry No 13589-04-3

ChEBI: ID 73615

ChemSpider: ID 5373137

EPA CompTox: ID DTXSID10874592

EROP-Moscow: ID E01332

J-GLOBAL: ID 200907099510465373

Metabolomics Workbench: ID 78914

Nikkaji: ID J81.650G

PubChem: CID 7009558

SATPdb: ID satpdb13539

SureChEMBL: ID SCHEMBL7609995

Wikidata: ID Q27141932