BIOPEP-UWM: Report

ID 10800
Name Inhibitor of tripeptidyl peptidase II
sequence
V{G[2!ph]}
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 250.2929 Monoisotopic mass 250.1313
IC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F.
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@H](C1=CC=CC=C1)C(=O)O

InChI=1S/C13H18N2O3/c1-8(2)10(14)12(16)15-11(13(17)18)9-6-4-3-5-7-9/h3-8,10-11H,14H2,1-2H3,(H,15,16)(H,17,18)/t10-,11-/m0/s1

InChIKey=MGXZWEUHMYIDTO-QWRGUYRKSA-N


{G[2!ph]} - Phenylglycine (ID 234 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand Val-phenylglycine-OH

ChEMBL: ID CHEMBL2371248

ChemSpider: ID 30846459

J-GLOBAL: ID 200907088277496539

Nikkaji: ID J2.464.261E

PubChem: CID: 73345550

ZINC: ID ZINC000013805186