BIOPEP-UWM: Report

ID 10835
Name Antithrombotic peptide
sequence
HKEMPFPK
Function:
Antithrombotic
 
Number of residues
8
Activity code
at
Activity :
antithrombotic
Chemical mass 1013.2116 Monoisotopic mass 1012.5148
EC50 :
0.00 µM


Bibliographic data:
Authors
Tu M., Feng L., Wang Z., Qiao M., Shahidi F., Lu W., Du M.
Title
Sequence analysis and molecular docking of antithrombotic peptides from casein hydrolysate by trypsin digestion. J. Funct. Foods, 32, 313-323, 2017
Year Source
2017 Journal


Additional information:
BIOPEP-UWM Virtual database

SMILES: N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCSC)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C47H72N12O11S/c1-71-24-19-34(55-42(64)33(17-18-39(60)61)54-41(63)32(13-5-7-20-48)53-40(62)31(50)26-30-27-51-28-52-30)45(67)58-22-9-16-38(58)44(66)57-36(25-29-11-3-2-4-12-29)46(68)59-23-10-15-37(59)43(65)56-35(47(69)70)14-6-8-21-49/h2-4,11-12,27-28,31-38H,5-10,13-26,48-50H2,1H3,(H,51,52)(H,53,62)(H,54,63)(H,55,64)(H,56,65)(H,57,66)(H,60,61)(H,69,70)/t31-,32-,33-,34-,35-,36-,37-,38-/m0/s1

InChIKey=PBQBGPKBTHCYMQ-QSVFAHTRSA-N


Bioactivity predicted using molecular docking



Antibacterial peptide according to the EROP-Moscow database; the MBPDB database


Database reference:
DFBP: ID DFBPANTH0158

EROP-Moscow: ID E24849

MBPDB: peptide HKEMPFPK