BIOPEP-UWM: Report

ID 10839
Name Inhibitor of tripeptidyl peptidase II
sequence
VM
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
2
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 248.3427 Monoisotopic mass 248.1190
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C10H20N2O3S/c1-6(2)8(11)9(13)12-7(10(14)15)4-5-16-3/h6-8H,4-5,11H2,1-3H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1

InChIKey=YSGSDAIMSCVPHG-YUMQZZPRSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8923); the EROP-Moscow database
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 9882)


Database reference:
BindingDB: ID 50085119

BIOPEP-UWM database of bioactive peptides: ID 8923; 9882

BRENDA: Ligand Val-Met-OH

CAS: Registry No 14486-09-0

ChEBI: ID 75015

ChemSpider: ID 5361146

DFBP: ID DFBPACEI1313

EROP-Moscow: ID E23995

FeptideDB: ID 7923

FooDB: ID FDB112135

HMDB: ID HMDB0029133

J-GLOBAL: ID 200907081349152886

Metabolomics Workbench: ID 79048

Nikkaji: ID J150.500I

PubChem: CID 6993039

SDBS: ID SDBS-9431

Wikidata: ID Q27145074

ZINC: ID ZINC1601795