BIOPEP-UWM: Report

ID 10848
Name Inhibitor of tripeptidyl peptidase II
sequence
VF{!OC2:0}
Function:
Inhibitor of tripeptidyl peptidase II (EC 3.4.14.10) (MEROPS ID: S08.090)
 
Number of residues
3
Activity code
tpp2
Activity :
inhibitor of tripeptidyl peptidase II
Chemical mass 292.3724 Monoisotopic mass 292.1781
EC50 :
0.00 µM


Bibliographic data:
Authors
Ganellin C. R., Bishop P. B., Bambal R. B., Chan S. M., Law J. K., Marabout B., Luthra P. M., Moore A. N., Peschard O., Bourgeat P., Rose C., Vargas F
Title
Inhibitors of tripeptidyl peptidase II. 2. Generation of the first novel lead inhibitor of cholecystokinin-8-inactivating peptidase: a strategy for the design of peptidase inhibitors. J. Med. Chem., 43, 664-674, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)OCC

InChI=1S/C16H24N2O3/c1-4-21-16(20)13(10-12-8-6-5-7-9-12)18-15(19)14(17)11(2)3/h5-9,11,13-14H,4,10,17H2,1-3H3,(H,18,19)/t13-,14-/m0/s1

InChIKey=SGKIAFQSYRXFHH-KBPBESRZSA-N


<!OC2:0> - Ethanol (C-terminal modification) (ID 106 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand Val-Phe-O(CH2)CH3

ChemSpider: ID 74108887

J-GLOBAL: ID 201707009375099071

Nikkaji: ID J3.589.959F

PubChem: CID 70051124

SureChEMBL: ID SCHEMBL7307372