BIOPEP-UWM: Report

ID 10879
Name Xanthine oxidase inhibitor
sequence
LWM
Function:
Inhibitor of Xanthine oxidase (EC 1.17.3.2)
 
Number of residues
3
Activity code
xox
Activity :
xanthine oxidase inhibitor
Chemical mass 448.5787 Monoisotopic mass 448.2137
IC50 :
5.01 µM


Bibliographic data:
Authors
Qi X., Chen H., Guan K., Sun Y., Wang R., Li Q., Ma Y.
Title
Novel xanthine oxidase inhibitory peptides derived from whey protein: identification, in vitro inhibition mechanism and in vivo activity validation. Bioorg. Chem., 128, 106097, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)N[C@@H](CCSC)C(=O)O

InChI=1S/C22H32N4O4S/c1-13(2)10-16(23)20(27)26-19(21(28)25-18(22(29)30)8-9-31-3)11-14-12-24-17-7-5-4-6-15(14)17/h4-7,12-13,16,18-19,24H,8-11,23H2,1-3H3,(H,25,28)(H,26,27)(H,29,30)/t16-,18-,19-/m0/s1

InChIKey=UIIMIKFNIYPDJF-WDSOQIARSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8013)
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9513)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8013; 9513

ChemSpider: ID 57567997

EPA DSSTox: ID DTXCID60513060

J-GLOBAL: ID 200907082174296630

Nikkaji: ID J343.949F

PubChem: CID 14619840