BIOPEP-UWM: Report

ID 10885
Name Hypotensive peptide
sequence
TF
Function:
Lowering blood pressure in rats
 
Number of residues
2
Activity code
hyp
Activity :
hypotensive
Chemical mass 266.2923 Monoisotopic mass 266.1262
IC50 :
0.00 µM


Bibliographic data:
Authors
He R., Malomo S. A., Alashi A., Girgih A. T., Ju X., Aluko R. E.
Title
Purification and hypotensive activity of rapeseed protein-derived renin and angiotensin converting enzyme inhibitory peptides. J. Funct. Foods, 5, 781-789, 2013
Year Source
2013 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C13H18N2O4/c1-8(16)11(14)12(17)15-10(13(18)19)7-9-5-3-2-4-6-9/h2-6,8,10-11,16H,7,14H2,1H3,(H,15,17)(H,18,19)/t8-,10+,11+/m1/s1

InChIKey=IQHUITKNHOKGFC-MIMYLULJSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 8185); the ChEMBL database; the DFBP database; the EROP-Moscow database; the PubChem database
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9486);
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8900)
Inhibitor of Renin (EC 3.4.23.15) (MEROPS ID: A01.007) according to the BIOPEP-UWM database of bioactive peptides (ID 9471); the DFBP database


Database reference:
AHTPDB: ID 1288, 1360, 1407, 1935, 2735, 2959, 3003, 4030, 4715, 5174, 5547, 6283, 6759

BindingDB: ID 50049727

BioPepDB: ID biopep01280

BIOPEP-UWM database of bioactive peptides: ID 8185; 8900; 9471; 9486

BRENDA: Ligand Thr-Phe

CAS: Registry No 16875-27-7

ChEBI: ID 74862

ChEMBL: ID CHEMBL3321993

ChemSpider: ID 5374146

DFBP: ID DFBPRENI0001; DFBPACEI1357; DFBPACEI1422; DFBPACEI1587; DFBPANHY0028; DFBPMUFU0339

EPA CompTox: ID DTXSID101346616

EROP-Moscow: ID E04068

HMDB: ID HMDB0029068

J-GLOBAL: ID 200907000712776838

Metabolights: ID MTBLC74862

Metabolomics Workbench: ID 78989

MoNA: ID MT000062

Nikkaji: ID J307.687C

PlantPepDB: ID PPepDB_3836

PubChem: CID 7010580

SATPdb: ID satpdb15566

SureChEMBL: ID SCHEMBL233445

Wikidata: ID Q27144972

ZINC: ID ZINC000002391070