BIOPEP-UWM: Report

ID 10905
Name Neprilysin inhibitor
sequence
AE
Function:
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001)
 
Number of residues
2
Activity code
nep
Activity :
neprilysin inhibitor
Chemical mass 218.2066 Monoisotopic mass 218.0899
EC50 :
0.00 µM


Bibliographic data:
Authors
Moreno-Mariscal C., Carrera-Alvarado G., Mora L., Toldrá F.
Title
Neprilysin (NEP) and Angiotensin Converting Enzyme-I (ACE-I) inhibitory dipeptides from chicken carcass hydrolysates. LWT, 221, 117591, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)CCC(=O)O)C

InChI=1S/C8H14N2O5/c1-4(9)7(13)10-5(8(14)15)2-3-6(11)12/h4-5H,2-3,9H2,1H3,(H,10,13)(H,11,12)(H,14,15)/t4-,5-/m0/s1

InChIKey=VYZAGTDAHUIRQA-WHFBIAKZSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8758)
Inhibitor of Glutamate carboxypeptidase II (EC 3.4.17.21) (MEROPS ID: M28.010) according to the BIOPEP-UWM database of bioactive peptides (ID 10635), the BRENDA database


Umami peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 349); the EROP-Moscow database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8758; 10635

BIOPEP-UWM database of sensory peptides and amino acids: ID 349

BRENDA: Ligand Ala-Glu

CAS: Registry No 13187-90-1

ChEBI: ID 61565

ChEMBL: ID CHEMBL2074938

ChemIDplus: ID 013187901

ChemSpider: ID 114174

EPA CompTox: ID DTXSID70927376

EROP-Moscow: ID E01841

FooDB: ID FDB111746

Good Scents: ID rw1301381

HMDB: ID HMDB0028686

J-GLOBAL: ID 200907068879915582

KEGG: ID C20958

Metabolomics Workbench: ID 78662

Nikkaji: ID J81.565I

PubChem: CID 128841

UniChem: ID 1104834

UNII: ID 8D40GXI4MA

Wikidata: ID Q27131168

ZINC: ID ZINC02242980