BIOPEP-UWM: Report

ID 10907
Name Neprilysin inhibitor
sequence
AR
Function:
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001)
 
Number of residues
2
Activity code
nep
Activity :
neprilysin inhibitor
Chemical mass 245.2781 Monoisotopic mass 245.1484
EC50 :
0.00 µM


Bibliographic data:
Authors
Moreno-Mariscal C., Carrera-Alvarado G., Mora L., Toldrá F.
Title
Neprilysin (NEP) and Angiotensin Converting Enzyme-I (ACE-I) inhibitory dipeptides from chicken carcass hydrolysates. LWT, 221, 117591, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

InChI=1S/C9H19N5O3/c1-5(10)7(15)14-6(8(16)17)3-2-4-13-9(11)12/h5-6H,2-4,10H2,1H3,(H,14,15)(H,16,17)(H4,11,12,13)/t5-,6-/m0/s1

InChIKey=SITWEMZOJNKJCH-WDSKDSINSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP-UWM database of bioactive peptides (ID 7742), the DFBP database, the EROP-Moscow database

Salty taste enhancing peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 421)


Database reference:
AHTPDB: ID 1699, 3274, 3891, 4704, 5136, 5870, 6110, 6690

BioPepDB: ID 7742

BIOPEP-UWM database of biactive peptides: ID 7742

BIOPEP-UWM database of sensory peptides and amino acids: ID 421

BRENDA: Ligand Ala-Arg

CAS: Registry No 16709-12-9

ChEBI: ID 137238

ChemSpider: ID 393568

DFBP: ID DFBPACEI0224

EPA CompTox: ID DTXSID60332213

EROP-Moscow: ID E14726

FooDB: ID FDB111741

HMDB: ID HMDB0028681

J-GLOBAL: ID 200907044095231737

Metabolomics Workbench: ID 78657

MMDB: ID 1253.4

Nikkaji: ID J82.535B

PubChem: CID 446132

SATPdb: ID satpdb15773

SureChEMBL: ID SCHEMBL2490761

UniChem: ID 25075270

Wikidata: ID Q82096759

ZINC: ID ZINC02579085