BIOPEP-UWM: Report

ID 10909
Name Neprilysin inhibitor
sequence
ER
Function:
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001)
 
Number of residues
2
Activity code
nep
Activity :
neprilysin inhibitor
Chemical mass 303.3141 Monoisotopic mass 303.1538
EC50 :
0.00 µM


Bibliographic data:
Authors
Moreno-Mariscal C., Carrera-Alvarado G., Mora L., Toldrá F.
Title
Neprilysin (NEP) and Angiotensin Converting Enzyme-I (ACE-I) inhibitory dipeptides from chicken carcass hydrolysates. LWT, 221, 117591, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI= 1S/C11H21N5O5/c12-6(3-4-8(17)18)9(19)16-7(10(20)21)2-1-5-15-11(13)14/h6-7H,1-5,12H2,(H,16,19)(H,17,18)(H,20,21)(H4,13,14,15)/t6-,7-/m0/s1

InChIKey=MPZWMIIOPAPAKE-BQBZGAKWSA-N


Inhibitor of angiotensin I-converting enzyme (EC 3.4.15.1; MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP-UWM database of bioactive peptides (ID 9944), the DFBP database, the EROP-Moscow database


Database reference:
AHTPDB: ID 2708, 4719, 5144, 6115

BioPepDB: ID biopep00188

BIOPEP-UWM database of bioactive peptides: ID 9944

CAS: Registry No 7219-59-2

ChemSpider: ID 7972216

ChEBI: ID 157844

DFBP: ID DFBPACEI1244, DFBPANHY0078, DFBPMUFU0274

EPA CompTox: ID DTXSID701313893

EROP-Moscow: ID E09356

FooDB: ID FDB111858

HMDB: ID HMDB0028813

Metabolomics Workbench: ID 78777

PubChem: CID 9796450

SATPdb: ID satpdb22163

SureChEMBL: ID SCHEMBL1090558