BIOPEP-UWM: Report

ID 10910
Name Neprilysin inhibitor
sequence
GD
Function:
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001)
 
Number of residues
2
Activity code
nep
Activity :
neprilysin inhibitor
Chemical mass 190.1536 Monoisotopic mass 190.0587
EC50 :
0.00 µM


Bibliographic data:
Authors
Moreno-Mariscal C., Carrera-Alvarado G., Mora L., Toldrá F.
Title
Neprilysin (NEP) and Angiotensin Converting Enzyme-I (ACE-I) inhibitory dipeptides from chicken carcass hydrolysates. LWT, 221, 117591, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)O

InChI=1S/C6H10N2O5/c7-2-4(9)8-3(6(12)13)1-5(10)11/h3H,1-2,7H2,(H,8,9)(H,10,11)(H,12,13)/t3-/m0/s1

InChIKey=SCCPDJAQCXWPTF-VKHMYHEASA-N


Inhibitor of angiotensin I-converting enzyme (EC 3.4.15.1; MEROPS ID: M02-001) according to the AHTPDB database, the BIOPEP-UWM database of bioactive peptides (ID 7620), the ChEMBL database, the DFBP database, the EROP-Moscow database


Database reference:
AHTPDB: ID 1476, 1693, 3059, 3092, 3096, 3252, 3823, 3915, 4400, 4529, 4657, 6607

BindingDB: ID 50188493

BIOPEP-UWM database of bioactive peptides: ID 7620

CAS: Registry No 4685-12-5

ChEBI: ID 73804

ChEMBL: ID CHEMBL91392

ChemSpider: ID 87881

DFBP: ID DFBPACEI1629

ECHA: 225-140-1

EROP-Moscow: ID E10390

FooDB: ID FDB111876

HMDB: ID HMDB0028837

J-GLOBAL: ID 200907049288254043

Metabolomics Workbench: ID 78799

Nikkaji: ID J149.619K

PlantPepDB: ID PPepDB_51

PubChem: CID 97363

SATPdb: ID satpdb27666

SureChEMBL: ID SCHEMBL3207709

UniChem: ID 546586

Wikidata: ID Q27144120

ZINC: ID ZINC000001708196