BIOPEP-UWM: Report

ID 10912
Name Neprilysin inhibitor
sequence
GG
Function:
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001)
 
Number of residues
2
Activity code
nep
Activity :
neprilysin inhibitor
Chemical mass 132.1176 Monoisotopic mass 132.0533
EC50 :
0.00 µM


Bibliographic data:
Authors
Moreno-Mariscal C., Carrera-Alvarado G., Mora L., Toldrá F.
Title
Neprilysin (NEP) and Angiotensin Converting Enzyme-I (ACE-I) inhibitory dipeptides from chicken carcass hydrolysates. LWT, 221, 117591, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: NCC(=O)NCC(=O)O
InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
InChIKey=YMAWOPBAYDPSLA-UHFFFAOYSA-N

Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM dtabase of bioactive peptides (ID 8783)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, BIOPEP-UWM database of bioactive peptides (ID 7616), the ChEMBL database, the DFBP database, the EROP-Moscow database


Database reference:
AHTPDB: ID 1371, 1475, 2995, 3014, 3036, 3044, 3069, 3126, 3129, 3248, 3313, ahtpdb_3557, 3819, 3919, 4404, 4525, 4703, 6602

BindingDB: ID 50169222

BioCyc: ID GLYCYLGLYCINE

BIOPEP-UWM database of bioactive peptides: ID 7616, 8783

CAS: Registry No 556-50-3

ChEBI ID 17201

ChEMBL: ID CHEMBL292467

Chemspider: ID 10690

DFBP: ID DFBPACEI1353

ECHA: ID 209-127-8

EPA CompTox: ID DTXSID90862194

EROP-Moscow: ID E10389

FooDB: ID FDB028413

Golm Metabolome Database: ID 33903968-DDB2-47F2-9B6C-7C232D1962DA

HMDB: ID HMDB0011733

KEGG: ID C02037

J-GLOBAL: ID 200907052080333889

KNApSAcK: ID C00053264

MeSH: Terms Diglycine, Glycyl Glycine, Glycyl-Glycine, Glycylglycine

Metabolomics Workbench: ID 71575

Milk Composition Database: ID BMDB11733

NIAID: ID 018854

Nikkaji: ID J2.659J

NMRShiftDB: ID 10016979

PubChem: CID 11163

Sabio-RK: ID 255572362

SATPdb: ID satpdb12484

UNII: ID 10525P22U0

Wikidata: ID Q10634568