BIOPEP-UWM: Report

ID 10921
Name ACE inhibitor
sequence
KK
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 274.3588 Monoisotopic mass 274.1999
IC50 :
0.00 µM


Bibliographic data:
Authors
Moreno-Mariscal C., Carrera-Alvarado G., Mora L., Toldrá F.
Title
Neprilysin (NEP) and Angiotensin Converting Enzyme-I (ACE-I) inhibitory dipeptides from chicken carcass hydrolysates. LWT, 221, 117591, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(O)=O

InChI=1S/C12H26N4O3/c13-7-3-1-5-9(15)11(17)16-10(12(18)19)6-2-4-8-14/h9-10H,1-8,13-15H2,(H,16,17)(H,18,19)/t9-,10-/m0/s1

InChIKey=NVGBPTNZLWRQSY-UWVGGRQHSA-N

Inhibitor of dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8522);
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001) according to the BIOPEP-UWM database of bioactive peptides
Bacterial permease ligand according to the BIOPEP-UWM database (ID 3751)


Database reference:
ACToR: ID 13184-13-9

BindingDB: ID 50188512

BIOPEP-UWM database of bioactive peptides: ID 3751, 8813

BRENDA: Ligand L-Lys-L-Lys

CAS: Registry No 13184-13-9

ChEBI: ID 74564

ChEMBL: ID CHEMBL379332

ChemSpider: ID 114170

EPA CompTox: ID DTXSID00927364

EROP-Moscow: ID E09291

FooDB: ID FDB111979

HMDB: ID HMDB0028956

J-GLOBAL: ID 200907051674543321

Metabolights: ID MTBLC74564

Metabolomics Workbench: ID 78887

MMDB: ID 6217.2

Nikkaji: ID J81.564K

PlantPepDB: ID PPepDB_2579

PubChem: CID 128837

SureChEMBL: ID SCHEMBL1070057

UniChem: ID 378249

UNII: ID 96TER1JROC

Wikidata: ID Q27144740

ZINC: ID ZINC000002043137