BIOPEP-UWM: Report

ID 10983
Name Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
AAQEKIRYW
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
9
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 1164.3098 Monoisotopic mass 1163.6069
IC50 :
0.00 µM


Bibliographic data:
Authors
Xu Y., Pei Y., Liu Z., Tan P., Liu R., Chu L., Zhang Y., Wang W., Wang H.
Title
Discovery of novel DPP4 inhibitory peptides from egg yolk by machine learning and molecular docking: In vitro and in vivo validation. Food Chem., 476, 143412, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C54H81N15O14/c1-5-28(2)44(69-50(79)36(13-8-9-23-55)64-49(78)39(20-22-43(72)73)65-48(77)38(19-21-42(57)71)63-46(75)30(4)62-45(74)29(3)56)52(81)66-37(14-10-24-60-54(58)59)47(76)67-40(25-31-15-17-33(70)18-16-31)51(80)68-41(53(82)83)26-32-27-61-35-12-7-6-11-34(32)35/h6-7,11-12,15-18,27-30,36-41,44,61,70H,5,8-10,13-14,19-26,55-56H2,1-4H3,(H2,57,71)(H,62,74)(H,63,75)(H,64,78)(H,65,77)(H,66,81)(H,67,76)(H,68,80)(H,69,79)(H,72,73)(H,82,83)(H4,58,59,60)/t28-,29-,30-,36-,37-,38-,39-,40-,41-,44-/m0/s1

InChIKey=HUKSXEHEMIRYIO-DGGJFMSGSA-N


Database reference: