BIOPEP-UWM: Report

ID 10987
Name Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
RYHFPEGL
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
8
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 1018.1228 Monoisotopic mass 1017.5017
IC50 :
0.00 µM


Bibliographic data:
Authors
Xu Y., Pei Y., Liu Z., Tan P., Liu R., Chu L., Zhang Y., Wang W., Wang H.
Title
Discovery of novel DPP4 inhibitory peptides from egg yolk by machine learning and molecular docking: In vitro and in vivo validation. Food Chem., 476, 143412, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C48H67N13O12/c1-27(2)20-37(47(72)73)56-39(63)25-54-42(67)33(16-17-40(64)65)57-45(70)38-11-7-19-61(38)46(71)36(22-28-8-4-3-5-9-28)60-44(69)35(23-30-24-52-26-55-30)59-43(68)34(21-29-12-14-31(62)15-13-29)58-41(66)32(49)10-6-18-53-48(50)51/h3-5,8-9,12-15,24,26-27,32-38,62H,6-7,10-11,16-23,25,49H2,1-2H3,(H,52,55)(H,54,67)(H,56,63)(H,57,70)(H,58,66)(H,59,68)(H,60,69)(H,64,65)(H,72,73)(H4,50,51,53)/t32-,33-,34-,35-,36-,37-,38-/m0/s1

InChIKey=DILAROGFKFYGCO-CXWHUAPYSA-N


Database reference: