BIOPEP-UWM: Report

ID 11014
Name ACE inhibitor
sequence
RWL
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 473.5671 Monoisotopic mass 473.2743
IC50 :
580.12 µM


Bibliographic data:
Authors
Zhu R., Zhang H., Wu Y., Li H., Tang H., Xu X., Zhao K.
Title
Exploration and molecular mechanism of novel ACE inhibitory peptides from goat milk protein: A combined in silico and in vitro study. Int. Dairy J., 167, 106265, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C23H35N7O4/c1-13(2)10-19(22(33)34)30-21(32)18(11-14-12-28-17-8-4-3-6-15(14)17)29-20(31)16(24)7-5-9-27-23(25)26/h3-4,6,8,12-13,16,18-19,28H,5,7,9-11,24H2,1-2H3,(H,29,31)(H,30,32)(H,33,34)(H4,25,26,27)/t16-,18-,19-/m0/s1

InChIKey=YHZQOSXDTFRZKU-WDSOQIARSA-N


Database reference:
ChEBI: ID 159378

Metabolomics Workbench: ID 79806

PubChem: CID 25069730

UniChem: ID 34579864

Wikidata: ID Q106027111