BIOPEP-UWM: Report

ID 11042
Name ACE inhibitor
sequence
GPAV

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 342.3897 Monoisotopic mass 342.1897
IC50 :
415.91 µM



Bibliographic data:
Authors
Neves A. C., Harnedy P. A., O’Keeffe M. B., FitzGerald R. J.
Title
Bioactive peptides from Atlantic salmon (Salmo salar) with angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory, and antioxidant activities. Food Chem., 218, 396–405, 2017
Year Source
2017 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)O

InChI=1S/C8H16N2O3S/c1-4(2)6(9)7(11)10-5(3-14)8(12)13/h4-6,14H,3,9H2,1-2H3,(H,10,11)(H,12,13)/t5-,6-/m0/s1

InChIKey=WPSXZFTVLIAPCN-WDSKDSINSA-N

Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides; the EROP-Moscow database



Database reference:
EROP-Moscow: ID E24048