BIOPEP-UWM: Report

ID 11044
Name Acetylcholinesterase inhibitor
sequence
LSPGV

Function:
Inhibitor of acetylcholinestrase (EC 3.1.1.7)
 
Number of residues
5
Activity code
ache
Activity :
AChE inhibitor
Chemical mass 471.5463 Monoisotopic mass 471.2684
IC50 :
7.32 µM



Bibliographic data:
Authors
Li Y., Gao S., Zhang X., Cao Z., Guo Y., Zhao R., Li L., Liu Y., Qin Q., Yi B., Zhao G.
Title
Efficient screening of synergistic antioxidant and AChE inhibitory peptides from sea cucumber (Stichopus japonicus) using a novel approach combining de novo sequencing and parallel peptide synthesis. Peptide Sci., 117, e70002, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)O

InChI=1S/C21H37N5O7/c1-11(2)8-13(22)18(29)24-14(10-27)20(31)26-7-5-6-15(26)19(30)23-9-16(28)25-17(12(3)4)21(32)33/h11-15,17,27H,5-10,22H2,1-4H3,(H,23,30)(H,24,29)(H,25,28)(H,32,33)/t13-5-,17-/m0/s1

InChIKey=TYGYYGLAOBALJW-AGOFZYAISA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides



Database reference: