BIOPEP-UWM: Report

ID 11049
Name Acetylcholinesterase inhibitor
sequence
FSWP

Function:
Inhibitor of acetylcholinestrase (EC 3.1.1.7)
 
Number of residues
4
Activity code
ache
Activity :
AChE inhibitor
Chemical mass 535.5902 Monoisotopic mass 535.2423
IC50 :
35.92 µM



Bibliographic data:
Authors
Li Y., Gao S., Zhang X., Cao Z., Guo Y., Zhao R., Li L., Liu Y., Qin Q., Yi B., Zhao G.
Title
Efficient screening of synergistic antioxidant and AChE inhibitory peptides from sea cucumber (Stichopus japonicus) using a novel approach combining de novo sequencing and parallel peptide synthesis. Peptide Sci., 117, e70002, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CO)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C28H33N5O6/c29-20(13-17-7-2-1-3-8-17)25(35)32-23(16-34)26(36)31-22(27(37)33-12-6-11-24(33)28(38)39)14-18-15-30-21-10-5-4-9-19(18)21/h1-5,7-10,15,20,22-24,30,34H,6,11-14,16,29H2,(H,31,36)(H,32,35)(H,38,39)/t20-,22-,23-,24-/m0/s1

InChIKey=CSMFIOOYXKRJSB-BIHRQFPBSA-N


Inhibitor of acetylcholinestrase (EC 3.1.1.7) according to the BIOPEP-UWM database of bioactive peptides



Database reference: